Joel Smolanoff

Associate Professor and Researcher
Biochemistry

Ph.D. - State University of New York at Buffalo

Office: Dominica
ph: 767-255-6228

Dr. Joel Smolanoff has a distinguished career as a biochemist. He was a postdoctoral fellow at Cornell University after receiving his PhD in organic chemistry the StateUniversity of New York at Buffalo. Dr. Smolanoff was a senior scientist with Rohm & Haas Inc in their Agricultural Chemicals Division and their Animal Health Division. He also was a partner, a consultant, and the director of research and development with Delaware Chemistries, Inc.

Dr. Smolanoff's research contributions have resulted in eleven patents. He pioneered the photochemical synthesis of novel odor elimination products. He also synthesized highly efficacious and low mammalian toxicity insect repellents for use on human and livestock, developed a low toxicity organophosphate insecticide for corn rootworm control, and developed novel order elimination products based on a natural product that binds small noxious organic molecules irreversibly.

Since Ross University School of Medicine in 1997 as an associate professor of biochemistry and researcher in bioorganic/medicinal chemistry, Dr. Smolanoff initiated a research project to design and synthesize novel inhibitors of HIV-1 Reverse Transcriptase, HIV-1 Integrase and the Retroviral Zinc Fingers on the Nucleocapsid p7 (Ncp7) protein. Two papers will be submitted for publication in peer-reviewed journals. The novel compounds will be submitted to the National Cancer Institute for HIV screening as well as screening in various tumor cell lines.

Dr. Smolanoff is a member of the American Chemical Society (Medicinal Chemistry Division), the American Chemical Society (Biochemistry Division) and the Society of Sigma Xi (a national honor society in chemistry).

Selected Publications:
J. Grogan and J. Smolanoff (2007)
Biocatalysts in the Synthesis of Chiral Drug Molecules, A Review Article for Current Opinion Medicinal Chemistry-Anticancer Drugs Manuscript in preparation

J. Smolanoff (2007)
Chemistry Letters, Synthesis of Novel Adamantyl-Substituted Uracils as Potential inhibitors of HIV-1 Reverse Transcriptase. x Manuscript in preparation

J. Smolanoff (2007)
Chemistry Letters, Synthesis of Novel Substituted Uracil Disulfides x Manuscript in preparation

J. Smolanoff, J. Meinwald and A. Duggan, J. Amer. (2007)
Chem. Soc 101, 5364 (1979).

J. Meinwald , J. Smolanoff and T. Eisner, J. (1975)
Chemical Ecology 1, 269

J. Smolanoff and J. Meinwald (1975)
Science 188, 734

J. Meinwald and J. Smolanoff (1975)
, , (1975). Tetrahedron Letters 28, 2367

A Padwa and J. Smolanoff (1975)
J. Amer. Chem. Soc 97, 4682

 

 

Back