Agnes Laville

Ph.D.- Professor, Associate Dean of Education
Biochemistry

B.Sc. - University of London
Ph.D. - University of London

Office: Dominica
ph: 767-255-6297

Dr. Agnes Laville has been with Ross University School of Medicine since 1998. She is a professor of biochemistry, Chair of the Academic Promotions Committee, and the Associate Dean of Education for Ross University. She also has participated in the Curriculum Committee and the Faculty Affairs Committee.

Her career began in clinical chemistry at St. Thomas Hospital Medical School, University of London, and Dr. Laville did her graduate student research in chemical pathology at the university. She conducted post-doctoral research at The United Medical and Dental Schools of Guys and St. Thomas, University of London. Dr. Laville then went to the University of Barcelona, where she was a research and development scientist and then a top grade biochemist. Dr. Laville focused on establishing appropriate methodologies for the clinical/scientific investigation of hyperlipidaemia and atherosclerosis. She also lectured in lipid metabolism and development of atherosclerosis in animal models and humans.

Dr. Laville received the Hoecsht Iberica award in 1994 for the best scientific publication ( La Ville A.E., Sola R., Balanya B., Turner P.R., Masana L. In vitro oxidised HDL is recognised by the scavenger receptor of macrophages: Implications for its protective role in vivo. Atherosclerosis (1994) 105 179-189). In 1997, she received a Bristol Myers Squibb award for a scientific project entitled: “ Metabolic changes in apolipoproteins A-1 and B-100 in subjects on diets rich in monounsaturated fatty acids (MUFA) and polyunsaturated fatty acids (PUFA), using stable isotopes. ( Congresso National de Atherosclerosis, Spain). In December 2006, Dr. Laville received the DeVry PRIDE award for excellence in teaching and service to her students.

Selected Publications:
Girona J, Laville AE, Sola R, Motta C, Masana L. (2003)
HDL derived from the different phases of conjugated diene formation reduces membrane fluidity and contributes to a decrease in free cholesterol efflux from human THP-1 macrophages. Biochim Biophys Acta. Sep 22;1633(3):143-8

Solans R, Motta C, Sola, R, Laville AE, Lima J, Simeon P, Montella N, Amadans-Gil L, Fonolosa V, Vilardel M. (2000)
Abnormalities of erythrocyte membrane fluidity, lipid composition, and lipid peroxidation in systemic sclerosis: evidence of free radical-mediated injury. Arthritis Rheum. Apr;43(4):894-900

Ribalta J., Girona J., Vallve JC., Laville AE., Heras M., Masana L . (1999)
Vitamin A is linked to the expression of the AI-CIII-AIV gene cluster in familial combined hyperlipidemia. J Lipid Res 40(3): 426-431.

Girona J., Laville AE., Sola R., Plana N., Masana L . (1999)
Simvastatin decreases aldehyde production derived from lipoprotein oxidation. Am J Cardiol 83(6): 846-851.

Girona J., Laville AE., Sola R., Masana L . (1998)
Caracterizacion fisico- Quimica y consecuencias metabolicas de las HDL oxidadas in vitro. Clin Invest Arteriosclerosis 10 : 2-10.

Ribalta J., Laville AE., Vallve JC., Girona J., Masana L . (1998)
Evidence against alterations in Lecithin : cholesterol acyltransferase (LCAT) activity in familial combined hyperlipidemia. Atherosclerosis 138: 383-389.

Laville AE., Sola R., Motta C., Plana N., Heras M., Ribalta J., Masana L. (1997)
Physiochemical changes in HDL3 after Bezafibrate treatment: influence on free cholesterol efflux from human fibroblasts. Cardiovasc Drug Ther 653-658

Girona J., Laville AE., Heras M., Olive S., Masana L.. (1997)
Oxidized lipoproteins including HDL and their lipid peroxidation products inhibit TNF-" secretion by THP 1 human macrophages. Free Radic Biol Med 23: 658-667.

Ribalta J., Laville AE., Girona J., Vallve JC., Masana L. (1997)
Low plasma vitamin A concentrations in familial combined hyperlipidemia. Clin Chem 43: 2379-2383.

 

 

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